平安! 发表于 2011-11-9 19:57
# S$ w& O, w7 p: BPazopanib (100 mg/kg/day free base equivalent) ; x' R; Y8 d' ~
这是个已经在美国上市的老药了,能下载到正式药物使用说明书英文版。
& X' G: O" `* b搜索了一下,原料一大堆。
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对不起!100mg/kg是用于移植瘤的,我弄错了。
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4 C4 Q/ H6 ^8 ~: R以下是正版说明书的推荐用量。6 v2 E& s3 ?+ F' Y4 I9 R! b$ j6 i
% G; |9 Q- ]+ j--------------------- DOSAGE AND ADMINISTRATION ----------------: y3 L0 ?" P M: c5 ?5 g9 `
* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1) - O6 c+ s. l& e
* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2) * R$ p/ l" k7 Y/ k3 [0 X
---------------------DOSAGE FORMS AND STRENGTHS --------------" ]. k( K! q1 _' P$ |# l |
200 mg tablets. (3)
# e, t% z# C7 L) }-------------------------------CONTRAINDICATIONS------------------------ |